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Symptoms of PBC. PBC does not always cause symptoms, but some people may experience: bone and joint aches; fatigue (extreme tiredness) itchy skin; ... Bile is a liquid produced inside。

When bile can’t flow properly through your biliary system, it affects all of these organs and vessels. Bile backs up in your bile ducts and organs, irritating the tissues and interfering with。

The biliary system—which includes the gallbladder and bile ducts—produces and transports bile leakage symptomsbile into the duodenum (the first part of the small intestine) to aid in digestion. A bile duct leak can。

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